Twelve years prior to the start of the story, the famous Hunter Ging Freecss left his infant son, Gon Freecss, with his cousin Mito on Whale Island. Gon, raised believing his parents were dead, finds out from Ging's apprentice, Kite, that his father is still alive. Gon then leaves his home to follow in his father's footsteps as a Hunter by taking the Hunter Exam. Prior to the Hunter Exam, Gon meets and befriends three of the other applicants, Kurapika, Killua Zoldyck, and Leorio. After the exam, Kurapika departs to find work and Leorio leaves to attend medical school. Gon and Killua decide to gain combat experience by training at the Heavens Arena, a 251-story building where over 4,000 fighters compete daily in fighting tournaments. There, they meet the kung-fu master, Wing, who teaches them about Nen--a chi-like life energy that can be used to manifest superhuman powers.

Game story:
A secretive cabal spirits away a sacred aura stone from hapless villagers and wreaks havoc on their collective constitution. To avoid certain disaster, Hunters spring into action to help recover the stolen aggregate of mineral matter. Amalgamating equal parts adventure and card battle, the latest HXH features animated battle screens where opponents duel with decks. Attacks, defense moves, and combination counters may be flipped out with the throw of a card. During the adventure portion of the game, Hunters may use various medical supplies, items, etc to help in the quest.